The Indianapolis Colts will travel to Tennessee for their first AFC South game of the 2015 season. Game time is set for 1 p.m. at Nissan Stadium in Nashville, Tenn.
The matchup will mark the 41st all-time meeting between the teams in the regular season, with the Colts holding a 27-13 advantage. Indianapolis has won the last seven contests against Tennessee dating back to 2011.
Last week, the Colts lost their regular season home opener against the New York Jets on Monday Night Football.
The Jets got off to a 10-0 halftime lead. The Colts were able to chip away at the deficit as the offense orchestrated an eight-play 91-yard drive at the beginning of the fourth quarter.