travel down I-65 to Nashville for a rematch with the Tennessee Titans (-2.5). This will be the fifth AFC South game the Colts have played in 2022, and it's Week 7. Every game the Colts play over the next ten weeks, with one bye sprinkled in, will be outside the division. It isn’t until Week 18 that the Colts have a chance to right the wrong that was the Week 1 tie in Houston.
What’s more, the Nashville game will either push the Titans further into an early AFC South lead, or it will flip the division in favor of the Colts.