The Indianapolis Colts are set to open the 2024 NFL season right where they left off against the Houston Texans at home from Lucas Oil. The teams and venue remain the same, but Colts fans are hoping for a different outcome. The Texans ended an unexpectedly exciting season for the Colts in dramatic fashion. A failed conversion on fourth and short sent the Texans to the playoffs with the division championship. FanDuel Sportsbook has the Colts as 2.5-point underdogs, so they will have an uphill battle to start.
The current money line sits at +132 with the over/under at 49.