After not missing a game in his NFL career, Indianapolis Colts guard Quenton Nelson will be out for at least three after being placed on injured reserve Saturday with a high right ankle sprain.
Nelson had already been set to miss his first game since entering the NFL as the No. 6 pick in the 2018 draft when he was ruled out against the Miami Dolphins on Friday. He had started 51 games, plus three playoff contests, prior to this week.
He suffered the ankle injury in the first half of the Colts' Week 3 loss at the Tennessee Titans.