The Indianapolis Colts are set to play their biggest game of the season as they square off against the Denver Broncos from Empower Field on Sunday. Each team is coming off byes having logged wins in their game before the break. Additionally, both are fighting for a playoff spot. The Broncos are currently holding down the seventh spot while the Colts are on the outside looking in from eighth. FanDuel Sportsbook is giving the home team an edge in this one with a 4.5 spread advantage.
The money line is starting at +188 with the over/under coming in at 43.