Luton made it 10 games unbeaten in the second-tier for the first time since their Division Two title-winning season of 1981-82 with Saturday's win at Rotherham.
Standing in their way of 11 and a step closer to the play-off places are relegation-threatened Reading, who with interim boss Noel Hunt in charge earned a point from league leaders Burnley on Saturday.
The visitors are currently third and a win would take them to 77 points, almost out of the clutches of the chasing play-off place pack.
Reading, in 22nd by virtue of a points deduction, have to get their own job done whilst relying on Luton's fiercest rivals Watford against Cardiff and also praying for good news from Norwich who travel to strugglers QPR.