As shaky as the quarterback play is likely to be in the AFC South, the running back matchups might be the premier matchups in the entire NFL. Both Jonathan Taylor and Derrick Henry have led the league in rushing and put together absolutely dominant seasons. Travis Etienne emerged last season as a consistent threat in Jacksonville. Dameon Pierce might be the fourth best back in the division and he’s pretty damn good.
Of course, fantasy projections tell you a lot of things, but they don’t tell you everything. Most teams employ at least three backs that get the ball over the course of a season.