Texans wide receiver Will Fuller was officially ruled out with a groin injury for Sunday's regular-season finale against the Titans.
The Texans are holding out hope that Fuller could return for a playoff game next week.
Meanwhile, quarterback Deshaun Watson is questionable with a back injury.
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If the Texans opt to rest Watson in a regular-season finale that may have no playoff seeding impact if the Chiefs beat the Chargers, then backup A.J. McCarron would fill in for him.
Watson's back injury isn't regarded as serious, but it would make sense to err on the side of caution to have him 100 percent healthy for the postseason.