Texans rookie inside linebacker Dylan Cole injured his hamstring during an interception return, and his return is questionable.
Cole got hurt after making an acrobatic interception of a pass from Cleveland Browns quarterback Kevin Hogan.
An undrafted rookie from Missouri State, Cole has two interceptions and one sack this season.
Meanwhile, Pro Bowl outside linebacker- defensive end Jadeveon Clowney returned to play after being shaken up previously and being attended to by trainers.
Clowney was able to walk off the field under his own power before going back into the game.