The Texans opened their 2012 season against the Miami Dolphins at Reliant Stadium with a decisive 30-10 win over the Dolphins.
Houston scored three touchdowns in the final minutes of the first half to take a 24-3 halftime lead the last time they faced Miami. scored two rushing touchdowns while the Texans defense forced four turnovers on four-consecutive possessions in the second quarter. , , and each had an interception in the game. finished with three pass deflections, two of which led to turnovers, and 1.5 sacks.