In the bottom of third inning, Springer fell behind 0-2 before popping a 1-2 curveball out to center.
Springer's line-drive single in the fourth nearly tied the game at 4, but Missions center fielder Alberth Martinez threw out Robert Pena at home.
Springer then scored the go-ahead run on a two-run double from No. 20 prospect Danry Vasquez as the Hooks plated six runs in the fourth for an 8-4 lead.
In his last plate appearance of the night, Springer struck out swinging on a 1-2 changeup from relief pitcher Adam Cimber in the bottom of the fifth.