Despite joining the American League over a decade ago, the Cincinnati Reds remain Houston’s most common opponent, and will remain so for at least another 40 years. With 850 meetings between the two, Houston’s next most common opponent is the San Francisco Giants, with 738 common games. Cincinnati owns a 449-401 edge for an Astros winning percentage of .472. That’s Houston’s 24th-best. In addition, Cincinnati has won the last six games of the series. The two have never met in the postseason.
Like I said, Houston has dropped the last six meetings in a row, including three in 2023 and three in 2019.