As with nearly all yearly interleague series, these two clubs will only meet for one series this season (unless they meet in the World Series). The last time The Astros and Cubs faced off was from May 15 through May 17 last season, when Houston swept the Northsiders at Minute Maid Park.
In the series finale, on May 17, J.P. France and the Astros spotted the Cubbies a 6-1 fourth-inning lead, holding the five-run deficit until the eighth inning before turning it on. Alex Bregman and Kyle Tucker each collected three hits, while Jeremy Peña, Jake Meyers, and Yainer Diaz also finished with multiple hits.