The Rangers finish the season with a 15-4 record against the Astros, tying for their second most wins against any opponent in club history. They were 17-2 against the Astros in 2013 and 53-23 against them over the past four years.
The Rangers have 15 games left, including 12 at home, against the Athletics, Angels, Brewers and Rays. Those teams went into Wednesday a combined 77 games under .500.
Astros rookie right-hander Joe Musgrove, staked to a 3-1 lead after two innings and a 5-1 lead in the sixth, held the Rangers to three runs in 6 1/3 innings.