It's hard to whittle down the top moments to just 10, but here's our stab at it, in chronological order:
1. Without Lance Berkman, who was out for more than a month after offseason knee surgery, the Astros had one of their worst starts in history at 15-30. They had a total of two wins on the road through May 24. The Houston Chronicle printed a picture of a tombstone and declared the Astros dead for 2005.
"When that tombstone article came out and we were 15-30, I told [manager Phil] Garner, 'We'll win 50 before we lose 50,'" said Doug Mansolino, who coached third base that season.