Week 2 of the NFL preseason was tough on quarterbacks, as both Buffalo and Philadelphia are dealing with injuries to potential Week 1 starters. Meanwhile, the Patriots lost one of their first-round picks for the season and the 49ers' starting running back could be sidelined until the regular season begins.
Here are the most important injuries that have occurred so far in the second week of preseason games:
Buffalo Bills
Quarterback AJ McCarron (broken collarbone)
Defensive tackle Kyle Williams (knee)
Prognosis: McCarron suffered a right shoulder injury, which is reportedly a hairline fracture to his right collarbone.