Football is a game that has hundreds of plays that determine the outcome. No single play determines a game. One play can certainly influence a game more than another play, but any one play by itself does not decide which team wins and which team loses. I will never blame a loss on the refs for blowing one call, no matter when it is made in the game, it just doesn't work that way. I will certainly be pissed off about a call, but I won't blame a loss entirely on the referees.
While the game is played between two teams, every game is heavily influenced by the refereeing, no matter what.