The NFL's most productive receiver is dealing with turf toe, and it didn't improve enough to get him on the field for the Falcons (7-5).
Jones has 72 catches for a league-best 1,253 yards - 165 yards more than the closest receiver.
Jones' absence is a boost for the Rams' beleaguered defense, as is the absence of Mohamed Sanu, the Falcons' No. 2 receiver. Sanu, who is fighting a groin injury, has caught 49 passes for 521 yards and three touchdowns.
The Rams are missing two key defensive starters: Robert Quinn is missing his second game with a concussion, and E.