The Kansas City Chiefs' long unbeaten run finally came to an end at the hands of the Buffalo Bills in one of a number of statement wins in the NFL on Sunday.
After 15 straight wins the defending Super Bowl champions were outplayed in Buffalo as the Bills deservedly ran out 30-21 winners.
The Pittsburgh Steelers were also big winners as they beat arch rivals Baltimore despite not scoring a touchdown.
The Detroit Lions scored a half century against lowly Jacksonville as they continue to look the stand out side in the NFC, while the Green Bay Packers defeated Chicago on the last play of the game.