Peterson announced on Friday that he was ready to return after missing the previous 11 games with a torn meniscus in his right knee and was listed as active before the game on Sunday. The Vikings also activated center Joe Berger after he missed the previous two games with a concussion.
Safety Harrison Smith (ankle), cornerback Trae Waynes (concussion), right guard Brandon Fusco (concussion) and receiver Laquon Treadwell (hamstring) were out.
For the Colts, tight end Dwayne Allen (hip), safety T.J. Green (ankle), receiver Phillip Dorsett (groin) and defensive tackle Zach Kerr (concussion) are active after being listed as questionable on Friday.