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Cardinals RB James Conner (knee) to sit out finale vs. 49ers

Arizona Cardinals running back James Conner has been ruled out of Sunday's game against the San Francisco 49ers due to a knee injury, coach Jonathan Gannon said Wednesday. Conner, 29, initially sustained his injury in Arizona's 36-30 overtime loss to the Carolina Panthers on Dec. 22. He was able to play this past weekend, however he exited the Cardinals' 13-9 setback to the Los Angeles Rams after just four carries for 4 yards. Signed to a two-year contract extension in November, Conner recorded career-high totals in carries (236), rushing yards (1,094) and games played (16). He also had eight touchdowns for the Cardinals (7-9), who have lost five of their last six games heading into season finale against the 49ers (6-10) in Glendale, Ariz.