The home team secured the victory when Phil Mickelson knocked one in the water at the par-3 16th hole, conceding his match to Francesco Molinari right on the tee box. The home team held a 14+-9+ lead with three matches still on the course at Le Golf National.
Molinari became the first European player to go 5-0 in the competition since the current format was adapted in 1979.
The Americans came into Sunday facing a daunting 10-6 deficit, and there was a glimmer of hope when they closed to within a point midway through the afternoon.