For those of you who have never been, Miami is a unique experience. The different cultures that mix in the area accompanied by the free spirit of the city itself (which may or may not have something to do with drug money helping to fund the initial infrastructure. But Vegas did the same thing and everyone loves that place!) makes Miami feel unique to pretty much any other city you can visit.
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Ideally I recommend spending more than one weekend in Miami to get the full experience of the city.