All-time series record: FSU leads 14-4
First meeting: 1952; Doak Campbell Stadium; Louisville won 41-14
Most recent meeting: 2017; Doak Campbell Stadium; Louisville won 31-28
Largest margin of victory: 1953; Doak Campbell Stadium; FSU won 59-0
Cardinals’ bookend of series success
While not continuous like UF and Miami, the series with Louisville is one of the oldest in Florida State’s history. Louisville and FSU first matched up in 1952, the inaugural season in which the Seminoles played the majority of their games against what would today be considered “FBS” programs. In fact, FSU only played two programs prior to 1952 that are currently playing FBS football: Troy State (now known as Troy University) every year from 1947-1951 and the University of Miami in 1951.