The Pittsburgh Panthers are one of few teams around who can claim a standoff in their recent rivalry with Notre Dame, splitting the last eight meetings outright, going 5-2-1 against the spread over that span. The Panthers will go off as home dogs when they battle the Irish Saturday afternoon at Heinz Field.
Point spread: Fighting Irish opened as 7.5-point favorites, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
College football pick, via Odds Shark computer: 32.2-21.2 Fighting Irish
Why the Notre Dame Fighting Irish can cover the spread
Notre Dame is 7-1 this season, 6-2 ATS, after topping Temple last week 24-20.