George Pickens is arguably the biggest name on the Week 15 injury report, leaving managers to scramble to find a replacement for Pittsburgh's No. 1 wideout.
The waiver wire has plenty of options for those managers and others in similar situations, their lineups adversely affected by injuries at key positions.
From veteran receivers thriving with a new quarterback to a young running back finding increased success with every passing game, they are potential match-ups or playoff winners for managers still fielding teams in meaningful fantasy play.
Who are they and why are they worth your time?