Every year, star NFL players go down with injuries. It's an unfortunate part of the game.
In addition to Christian McCaffrey and Puka Nacua, Cooper Kupp, Isiah Pacheco and Deebo Samuel could miss multiple games.
If you have one or more of those players, this week's sleeper list could provide quality replacements for them.
Managers waiting for Jordan Love's return should consider a red-hot rental quarterback who could be a season keeper or trade asset to help fill a void at another position in need.
In Week 3, managers can find favorable matchups against a few of the league's worst pass defenses and backups who may emerge in place of injured starters.