Focus on Sport/Getty Images
The top pick in most fantasy football drafts will be closely monitored over the next few days.
Christian McCaffrey was officially listed with a calf/Achilles injury on the San Francisco 49ers injury report this week.
McCaffrey was kept out of most of training camp with a calf injury, but he has been a participant at practice this week ahead of the Monday night clash with the New York Jets.
Justin Herbert was the other major injury concern for fantasy football players coming out of the preseason.
The Los Angeles Chargers quarterback will be ready for Jim Harbaugh's first game as the team's head coach on Sunday.