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Christian McCaffrey will make his long-anticipated 2024 NFL regular-season debut in Week 10.
The San Francisco 49ers running back has been out with Achilles and calf injuries, but the time has come for one of the most popular fantasy football draft picks to take the field.
McCaffrey's first opponent is the Tampa Bay Buccaneers, who have allowed 4.9 yards per carry this season.
CeeDee Lamb will also be on the field Sunday for the Dallas Cowboys, but his production could take a hit with Dak Prescott out.
Below is a look at all of the significant injury news affecting fantasy football matchups in Week 10.