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- Derek Carr, QB, NO: Out (oblique), per New Orleans Football's Nick Underhill.
- Anthony Richardson. QB, IND: Out (oblique), per team injury report.
- Jonathan Taylor, RB, IND: Out (ankle), per team injury report.
- Josh Downs, WR, IND: Questionable (toe), per team injury report
- Michael Pittman Jr., WR, IND: Questionable (back), per team injury report.
- Nick Chubb, RB, CLE: Out (knee), per Cleveland.com's Mary Kay Cabot.
- Rhamondre Stevenson, RB, NE: Out (foot), per KPRC's Aaron Wilson.
- Bijan Robinson, RB, ATL: Full participant in Friday practice (hamstring), per ESPN.