New Everton signings Ashley Williams and Yannick Bolasie are set for their full debuts in the EFL Cup at home to Yeovil.
The pair came off the bench in Saturday's win at West Brom but are to be given a chance to impress from the off against the League Two side.
Striker Romelu Lukaku, who also made his first appearance of the season after a heel injury as a substitute at the Hawthorns, is set to lead the line.
"For them, it's really important to have game time," said manager Ronald Koeman.