AC Milan's Serie A meeting with Inter Milan at San Siro kicks off a fascinating week of derbies - one in which Manchester City can clinch the Premier League title.
Milan have lost just once in their last five games and host an Inter side that has won back-to-back victories on Wednesday night.
Saturday's Premier League action could see the race for the league title settled early if City can beat Manchester United in the Saturday evening kick-off at the Etihad.
Pep Guardiola's side will break the record previously set by United for the earliest title-winning date.