Jeimer Candelario, who left Tuesday's game with a jammed middle finger in his right hand, is not in the lineup on Wednesday night.
Ronny Rodriguez will start at third base for the Tigers. Niko Goodrum will play second base, pushing Dixon Machado out of the lineup.
Tigers injuries: Latest news, updates, expected dates of return
A running tally of the Tigers bumps, bruises and sprains in 2018.
Tigers lefty Blaine Hardy (2-0, 2.77 ERA) will face Red Sox lefty Eduardo Rodriguez (6-1, 3.88) at 7:10 p.