Miguel Cabrera's two-out single in the bottom of the fourth inning was only the second hit for the Tigers, who left him on to end the frame when Victor Martinez -- who had the team's first hit -- popped out to catcher Jason Castro.
After four innings, the pitcher's duel between left-handers Matt Boyd and Hector Santiago remains scoreless.
Twins go 1-2-3 in 4th
Matt Boyd, with his fifth strikeout of the game, set the Twins down in order in the top of the fourth inning.
Robbie Grossman, so far the only baserunner for the Twins, flew out to left field, before Jorge Polanco popped out to Dixon Machado in foul territory on a 2-0 pitch.