Michael Fulmer stranded a baserunner in the top of the fourth inning.
Albert Pujols reached on an infield single on a ball that shortstop Dixon Machado tried to barehand, while likely having enough time to field it with his glove.
But Pujols was stranded after Yunel Escobar and C.J. Cron both flew out to right field and Ben Revere lined out to second base to end the inning.
Going to the bottom of the fourth, the Tigers are still up 4-1.
Castellanos adds to Tigers lead in 3rd
Nicholas Castellanos got his second RBI of the game in the bottom of the third inning.