Javier Báez unloaded on a full-count curveball from Boston Red Sox left-hander Rich Hill in the third inning, sending the over the wall in right-center field for his fifth home run this season.
It also marked Báez's second homer in four games.
Báez recorded a first-inning triple, too, and scored two of the Detroit Tigers' three runs in Tuesday's 5-4 loss to the Red Sox at Fenway Park. The Tigers (26-42) have dropped back-to-back games in the three-game series.
Against four pitches, the Tigers tallied 11 hits and two walks. For the second night in a row, they posted more hits than the Red Sox.