While some teams have clinched playoff spots and thus have the luxury of resting their starters, others in win-and-in situations are dealing with injuries at key positions.
The Jacksonville Jaguars can win the AFC South if they win on the road against the Tennessee Titans, but they might have to do it without starting quarterback Trevor Lawrence. The Jaguars will wait until game time to see if his sprained right AC joint will allow him to throw the ball well enough to play.
The Tampa Bay Buccaneers can win the NFC South if they win on the road against the Carolina Panthers, and things look a little better for them with starting quarterback Baker Mayfield.