The NFL closes out Week 11 with a game south of the border, as the San Francisco 49ers (-9.5)
are taking on the Arizona Cardinals (+9.5) at Aztec Stadium in Mexico City, Mexico. While the 49ers lead the overall head-to-head series, the Cardinals won both matchups last season.
The 49ers possess a combination of above-average offensive skill players paired with an elite defense and are on a two-game winning streak since acquiring running back Christian McCaffrey. In those two games, McCaffrey has 132 rushing yards, two rushing touchdowns, 12 receptions for 94 receiving yards, a receiving touchdown, as well as a 34-yard pass that also went for a touchdown.