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Live updates: Lions vs. 49ers

A new era begins Sunday at Ford Field. Detroit Lions fans undoubtedly are hoping, in the long run, it's not a new error.

The Lions open the 2021 season at home against the San Francisco 49ers, marking the regular-season head-coaching debut of Dan Campbell, under first-year general manager Brad Holmes.

There's a new quarterback, too, in case you haven't heard.

The Lions are rebuilding — or, retooling — as they've gone four seasons without a playoff appearance, and even longer (1992) without a playoff victory.

Campbell and Co. get a daunting first test in the 49ers, who are coming off an injury-marred 6-10 season following a Super Bowl appearance in 2019.