Tion Green took a screen pass from Brad Kaaya and turned it into an entertaining 74-yard touchdown to cut the Lions deficit to 27-10 with 7:41 remaining.
Green danced through the Buffalo defense, making several defenders miss before reversing field to get through the secondary and finish off the play.
Green isn't going to make the Lions final roster, but he has shown a nice combination of power and vision to warrant a spot on the practice squad.
Bills running away from Lions
Jordan Johnson capped a 10-play, 80-yard drive with a 2-yard touchdown that puts Buffalo up 27-3 with 9:34 remaining in the final game of the preseason.