The San Diego Chargers will try to defeat the Detroit Lions for the seventh time in eight meetings, and cover the spread for the fifth time in six games between the teams, when they square off in the season opener at Qualcomm Stadium Sunday.
The Chargers will be kicking off what could be their last season in San Diego if they decide to move next year, giving them plenty of motivation to get a home victory here.
Point spread: Chargers opened as two-point favorites; the total was 46.5 early in the week, according to sportsbooks monitored by Odds Shark (line updates and matchup report).