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Detroit Lions: Too little, too late as new-look Lions fall to 49ers in season opener

Sep 12, 2021; Detroit, Michigan, USA; Detroit Lions wide receiver Tyrell Williams (6) catches the ball for a first down in the first quarter against the San Francisco 49ers at Ford Field. Mandatory Credit: David Reginek-USA TODAY Sports

They made it close after a struggling for three quarters. Still, too many mistakes cost the Detroit Lions as they embarked on a new journey after an offseason full of changes.

The Lions found themselves in an early double-digit hole and were never able to recover in a 41-33 loss against the San Francisco 49ers on Sunday at Ford Field.