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Detroit Lions draftees Levi Onwuzurike, Jermar Jefferson inactive vs. San Francisco 49ers

Two of the Detroit Lions' seven picks from April's NFL draft are inactive for the team's season opener today against the San Francisco 49ers (1 p.m., Fox).

Levi Onwuzurike, a second-round pick out of Washington, is out after being listed as questionable on the Lions' injury report. Onwuzurike missed most of the summer with back and hip injuries.

Seventh-round pick Jermar Jefferson also is inactive as the Lions' No. 4 running back.

Godwin Igwebuike, who plays a bigger role on special teams than Jefferson, is up as the Lions' No.