The game-day inactives for the game between the Denver Broncos and Los Angeles Chargers were: Zach Wilson, Riley Moss, Jaleel McLaughlin, Levi Wallace, Levelle Bailey, Frank Crum, and Matt Henningsen. Moss and McLaughlin were still injured, the rest were healthy scratches.
Offense
| Player | Pos | Num | Pct |
| Garett Bolles | T | 64 | 100% |
| Ben Powers | G | 64 | 100% |
| Quinn Meinerz | G | 64 | 100% |
| Mike McGlinchey | T | 64 | 100% |
| Luke Wattenberg | C | 64 | 100% |
| Bo Nix | QB | 64 | 100% |
| Courtland Sutton | WR | 58 | 91% |
| Devaughn Vele | WR | 36 | 56% |
| Javonte Williams | RB | 33 | 52% |
| Marvin Mims | WR | 30 | 47% |
| Lucas Krull | TE | 28 | 44% |
| Adam Trautman | TE | 28 | 44% |
| Troy Franklin | WR | 26 | 41% |
| Lil'Jordan Humphrey | WR | 23 | 36% |
| Nate Adkins | TE | 21 | 33% |
| Audric Estime | RB | 13 | 20% |
| Michael Burton | FB | 10 | 16% |
| Blake Watson | RB | 10 | 16% |
| Matt Peart | T | 4 | 6% |
The entire offensive line and Bo Nix played every offensive snap.