The Westgate SuperBook opened the Panthers as 5.5-point favorites over the Denver Broncos on Sunday. Other Las Vegas sports books went with a lower number.
Station Casinos' sports book opened the Panthers as four-point favorites. William Hill and CG Technology's Nevada books each went with Panthers -3.5. The line appeared to be settling at Carolina -4 late Sunday night.
The over/under is set at 44.5 for Super Bowl 50 on Feb. 7, in Santa Clara, California.
Newton and the Panthers were impressive in a 49-15 rout of the Arizona Cardinals in the NFC Championship Game.