After an exceptional career at the unheralded Indiana State University, Jonas Griffith went undrafted in the 2020 draft. He was signed by the San Francisco 49ers but cut in training camp. He spent time on the practice squads of Indianapolis and San Francisco but was not active in 2020.
In 2021 he was traded at the end of training camp to the Denver Broncos, where he started 4 games. In 2022 he earned a starting role, but missed 8 games due to injury. He then tore his ACL in training camp and missed all of the 2023 season.