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Judging biggest overreactions for NFL Week 10

JACKSONVILLE -- There was pretty much only one thing that went wrong for the 49ers on Sunday. Late in the game and up 27-3 on the Jaguars, they were trying their darndest to get running back Christian McCaffrey a touchdown, and they just couldn't get it done. McCaffrey entered the game on an NFL-record-tying streak of 17 straight games with at least one touchdown. But sole possession of the record was not meant to be. Instead, it was fullback Kyle Juszczyk who got the final score of the game -- the fourth different 49ers player to score in the 34-3 win over Jacksonville.