Wolves midfielder Mario Lemina sustained a minor hamstring problem on Saturday and will be assessed.
Wolves head coach Julen Lopetegui said another player has "a little problem" but wouldn't name him.
Sam Johnstone will again start in goal for Crystal Palace despite the return from injury of Vicente Guaita, who was an unused substitute at the weekend.
Wilfried Zaha and Nathaniel Clyne are expected back in training later this week as they near a comeback.
MATCH FACTS
Head-to-head
- Crystal Palace have earned four straight Premier League wins over Wolves.