Villarreal defeated Arsenal 2-1 thanks to a pair of first-half goals in the first leg of their Europa League semifinals matchup.
Manu Trigueros and Raul Albiol gave the Spanish hosts the upper hand in a match that saw the Gunners lose Dani Ceballos in the second half due to two yellow cards.
Just five minutes into the game, Trigueros pounced on a loose ball at the edge of the Arsenal box and unfurled a shot into the far post past keeper Bernd Leno.
El Submarino Amarillo, led by former Arsenal boss Unai Emery, doubled their lead in the 29th minute when Raul Albiol buried a shot into the net off a corner kick.