Richard Shaw's Under-23 side will take on Bristol City this afternoon for a 13.00 kick-off, and will lineup with a side that features first-team players such as Joel Ward, Scott Dann and Connor Wickham.
Wickham and Dann have both been recovering from long-term injuries of late and have returned to first-team training, but neither has featured in any of Palace's recent matches.
They will join Ward, Sullay Kaikai and Jairo Reidewald alongside Nya Kirby, Levi Lumeka and Ollie O'Dwyer.
Bristol travel to south London sitting two places behind the Eagles, but Shaw's Palace have an eight-point lead.